The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
May. 25, 2018
Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd., Zhenjiang, CN;
Dongfang Shi, Fremont, CA (US);
Jianghua Zhu, Zhenjiang, CN;
Jie Gu, Zhenjiang, CN;
Xi Cheng, Zhenjiang, CN;
Yan Yang, Zhenjiang, CN;
He Zhou, Zhenjiang, CN;
Pengfei Li, Zhenjiang, CN;
Fan Wu, Zhenjiang, CN;
JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD., Suzhou, CN;
Abstract
The present invention belongs to the field of medicinal chemistry. Specifically disclosed is a class of URAT1 inhibitors for promoting uric acid excretion, which are compounds as represented by the structure of formula (I) or pharmaceutically acceptable salts thereof. Experiments show that the compounds provided by the present invention have a very good inhibitory effect on the transport of uric acid by hURAT1 in HEK293 transfected cells, and that such compounds have a good application prospect in the treatment of hyperuricemia or gout.