The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
Jan. 11, 2019
Applicant:
Centaurus Therapeutics, Half Moon Bay, CA (US);
Inventors:
Donna L. Romero, San Francisco, CA (US);
Jeremy Blitzer, San Francisco, CA (US);
Assignee:
Centaurus Therapeutics, San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 213/75 (2006.01); C07D 213/76 (2006.01); C07D 241/04 (2006.01); C07D 405/12 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07D 213/75 (2013.01); C07D 213/76 (2013.01); C07D 241/04 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); A61K 9/0053 (2013.01); A61K 45/06 (2013.01);
Abstract
Disclosed herein are dihydroceramide desaturase 1 (Des1) inhibitor compounds and compositions, which are useful in the treatment of diseases, such as metabolic disorders, where inhibition of Des1 is expected to be therapeutic to a patient. Methods of inhibition of Des1 activity in a human or animal subject are also provided.