The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
Mar. 03, 2021
Applicants:
Immunesensor Therapeutics, Inc., Dallas, TX (US);
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Boyu Zhong, Irving, TX (US);
Lijun Sun, Dallas, TX (US);
Heping Shi, Coppell, TX (US);
Jing Li, Beijing, CN;
Chuo Chen, Dallas, TX (US);
Zhijian Chen, Dallas, TX (US);
Assignees:
IMMUNESENSOR THERAPEUTICS, INC., Dallas, TX (US);
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/34 (2006.01); C07D 417/14 (2006.01); A61K 31/429 (2006.01); A61K 31/4365 (2006.01); A61K 31/4439 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); A61K 31/427 (2006.01); C07D 277/40 (2006.01); A61K 31/437 (2006.01); A61K 31/426 (2006.01); A61K 31/381 (2006.01); A61K 31/433 (2006.01); A61K 31/4709 (2006.01); A61K 39/39 (2006.01); A61K 45/06 (2006.01); A61K 31/454 (2006.01); A61K 31/4725 (2006.01); A61K 31/497 (2006.01); A61K 31/4985 (2006.01); A61K 31/501 (2006.01); C07D 277/36 (2006.01); C07D 403/06 (2006.01); C07D 417/04 (2006.01); C07D 417/06 (2006.01); C07D 417/10 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 277/34 (2013.01); A61K 31/381 (2013.01); A61K 31/426 (2013.01); A61K 31/427 (2013.01); A61K 31/429 (2013.01); A61K 31/433 (2013.01); A61K 31/437 (2013.01); A61K 31/4365 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/4709 (2013.01); A61K 31/4725 (2013.01); A61K 31/497 (2013.01); A61K 31/4985 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); A61K 39/39 (2013.01); A61K 45/06 (2013.01); C07D 277/36 (2013.01); C07D 277/40 (2013.01); C07D 403/06 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01); C07D 513/04 (2013.01);
Abstract
Disclosed are novel compounds of Formula I that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.