The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2023

Filed:

May. 18, 2020
Applicant:

Resilience Government Services, Inc., La Jolla, CA (US);

Inventors:

Ron Cobb, Gainesville, FL (US);

Michael Springer, Foxborough, MA (US);

Yawei Ni, College Station, TX (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/295 (2006.01); A61K 9/16 (2006.01); A61K 9/19 (2006.01); A61K 9/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 9/0095 (2013.01); A61K 9/1694 (2013.01); A61K 9/19 (2013.01); A61K 39/00 (2013.01); A61K 39/295 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/541 (2013.01); A61K 2039/55583 (2013.01); A61K 2039/70 (2013.01); C12N 2770/16023 (2013.01); C12N 2770/16034 (2013.01); C12N 2770/16071 (2013.01);
Abstract

A dry powder norovirus vaccine is provided, which comprises at least two norovirus antigens representing different genogroups. The vaccine may be produced by formulation with a mixture of different antigens or combination of monovalent powders with each containing one antigen. The formulated vaccine is suitable for mucosal administration and soluble in aqueous solutions for parenteral administration. A method of immunization is also provided, which comprises at least one administration of the vaccine via mucosal and/or parental route. The immunization may have multiple administrations of the vaccine, i.e., one or more immunizations via a mucosal route followed by one or more immunizations via a parenteral route or vice versa, to maximize both mucosal and systemic immune responses and protection against norovirus infections.


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