The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
Oct. 19, 2018
Applicant:
Crage Medical Co., Limited, Hong Kong, CN;
Inventors:
Zonghai Li, Shanghai, CN;
Huiping Gao, Shanghai, CN;
Peng Wang, Shanghai, CN;
Hua Jiang, Shanghai, CN;
Huamao Wang, Shanghai, CN;
Assignee:
CRAGE MEDICAL CO., LIMITED, Hong Kong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); A61K 48/00 (2006.01); C07K 16/30 (2006.01); C07K 14/725 (2006.01); A61K 9/00 (2006.01); A61K 31/519 (2006.01); A61K 31/664 (2006.01); A61K 31/7048 (2006.01); A61K 31/7076 (2006.01); A61K 38/20 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 9/0019 (2013.01); A61K 31/519 (2013.01); A61K 31/664 (2013.01); A61K 31/7048 (2013.01); A61K 31/7076 (2013.01); A61K 38/202 (2013.01); A61K 38/204 (2013.01); A61K 38/2013 (2013.01); A61K 38/2073 (2013.01); A61K 48/00 (2013.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 16/303 (2013.01); A01K 2207/12 (2013.01); A01K 2227/105 (2013.01); C07K 2317/24 (2013.01); C07K 2317/622 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01); C12N 2740/16043 (2013.01);
Abstract
Disclosed herein are methods of treating a subject exhibiting a solid tumor that expresses Glypican-3 (GPC3). The methods typically utilize g GPC3 chimeric antigen receptor immunoresponsive cells to a subject in need thereof to effect killing of tumor cells.