The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
Jan. 14, 2015
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventors:
Shelley L. Berger, Wayne, PA (US);
Xianxin Hua, Wynnewood, PA (US);
Morgan Sammons, Philadelphia, PA (US);
Jiajun Zhu, Philadelphia, PA (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/136 (2006.01); A61K 31/519 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/136 (2013.01); A61K 31/519 (2013.01); A61K 31/713 (2013.01);
Abstract
The present invention provides compositions and methods for treating and preventing cancer. The invention comprises an inhibitor of epigenetic regulators, including MLL1, MLL2, MOZ, menin, WDR5, or a combination thereof. In one embodiment, the invention provides a personalized method of treating a cancer as dependent upon its epigenetic signature.