The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2023

Filed:

Feb. 28, 2018
Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

John A. Copland, III, Ponte Vedra Beach, FL (US);

Christina Von Roemeling, Jacksonville, FL (US);

Han W. Tun, Jacksonville, FL (US);

Thomas R. Caulfield, Jacksonville, FL (US);

Yon Son Kim, Jacksonville Beach, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 31/4545 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61K 31/496 (2006.01); A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/4545 (2013.01); A61K 31/495 (2013.01); A61K 39/39541 (2013.01); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01);
Abstract

The present application provides methods and compositions for treating cancer, for example, renal cell carcinoma, melanoma, ovarian, breast, prostate, colon, pancreatic, bladder, liver, lung, and thyroid cancer, and more particularly to using an inhibitor of a stearoyl-Coenzyme A desaturase 1 (SCD1) enzyme in combination with a checkpoint inhibitor to treat these disorders.


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