The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Nov. 02, 2016
Applicants:
Board of Regents, the University of Texas System, Austin, TX (US);
Memgen, Llc, Houston, TX (US);
Inventors:
Willem W. Overwijk, Houston, TX (US);
Manisha Singh, Houston, TX (US);
Patrick Hwu, Houston, TX (US);
Mark Cantwell, San Diego, CA (US);
Assignees:
MEMGEN, Inc., Houston, TX (US);
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 16/28 (2006.01); A61P 35/04 (2006.01); A61K 9/00 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); G08G 1/14 (2006.01); G08G 1/01 (2006.01); H04L 67/02 (2022.01); H04W 4/02 (2018.01); H04L 67/306 (2022.01);
U.S. Cl.
CPC ...
G08G 1/144 (2013.01); A61K 9/0019 (2013.01); A61K 38/177 (2013.01); A61K 45/06 (2013.01); A61P 35/04 (2018.01); C07K 16/2818 (2013.01); C12N 15/86 (2013.01); G08G 1/0112 (2013.01); G08G 1/0129 (2013.01); G08G 1/0141 (2013.01); G08G 1/147 (2013.01); H04L 67/02 (2013.01); H04W 4/023 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/54 (2013.01); A61K 2039/55 (2013.01); C07K 2317/76 (2013.01); H04L 67/306 (2013.01);
Abstract
Provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of at least one immune checkpoint inhibitor and a chimeric CD 154 polypeptide. Also provided herein are methods of enhanced immune function.