The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Sep. 11, 2020
Applicant:
Laboratory Corporation of America Holdings, Burlington, NC (US);
Inventors:
Stephen E. Erickson, White Bear Township, MN (US);
Jose S. Gil, Winnetka, CA (US);
Wendy Hahn, Hugo, MN (US);
Dwight L. Anderson, Minneapolis, MN (US);
Assignee:
Laboratory Corporation of America Holdings, Burlington, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/04 (2006.01); C12Q 1/66 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/04 (2013.01); C12Q 1/66 (2013.01); G01N 2333/005 (2013.01); G01N 2333/90241 (2013.01);
Abstract
Disclosed herein are methods and systems for rapid detection of microorganisms such as bacteria in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene encoding one subunit of an indicator protein. The specificity of the bacteriophage allows detection of a particular bacteria of interest and an indicator signal may be amplified to optimize assay sensitivity.