The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

Sep. 28, 2018
Applicant:

Industry-university Cooperation Foundation Hanyang University, Seoul, KR;

Inventors:

Jin-Won Lee, Seoul, KR;

Myung Chan Gye, Gyeonggi-do, KR;

Su-Hyun Ryu, Gyeonggi-do, KR;

Young-Pil Kim, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01); C12Q 1/02 (2006.01); C07K 14/47 (2006.01); C12N 15/70 (2006.01); C07K 14/72 (2006.01); C07K 14/245 (2006.01); C07K 14/195 (2006.01); G01N 33/52 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/025 (2013.01); C07K 14/195 (2013.01); C07K 14/245 (2013.01); C07K 14/4702 (2013.01); C07K 14/72 (2013.01); C07K 14/721 (2013.01); C12N 15/70 (2013.01); C12N 15/74 (2013.01); C12Q 1/02 (2013.01); G01N 33/52 (2013.01); C07K 2319/43 (2013.01);
Abstract

The present invention relates to a genetically mutated bacteria strain for detecting an estrogenic compound and a method for detecting an estrogenic compound by using the same. More specifically, the present invention relates to a bacteria strain having an ability to detect an estrogenic compound, transformed by plasmid A comprising base sequences in which a gene for encoding a coactivator interacting with an estrogen receptor ligand binding domain (ER LBD) is conjugated to a gene for encoding λCI protein, and plasmid B in which a gene for encoding an estrogen receptor ligand binding domain (ER LBD) is conjugated to a gene for encoding αNTD protein, and a method for detecting an estrogenic compound by using same. The present invention can provide genetically mutated bacteria for detecting an estrogenic compound and a method for detecting an estrogenic compound by using same since the bacteria are based on estrogen receptor protein originated from the human body, and thus are environmentally friendly, and the detection of the bacteria can be performed in a very short time with low cost and labor by virtue of a relatively simple process.


Find Patent Forward Citations

Loading…