The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Apr. 03, 2018
Fundació Institut DE Recerca Biomèdica (Irb Barcelona), Barcelona, ES;
Institució Catalana DE Recerca I Estudis Avançats, Barcelona, ES;
Roger Gomis, Barcelona, ES;
Anna Arnal, Barcelona, ES;
Maria Tarragona, Barcelona, ES;
Milica Pavlovic, Lajkovac, RS;
Evarist Planet, Barcelona, ES;
Fundació Institut de Recerca Biomèdica (IRB Barcelona), Barcelona, ES;
Institució Catalana de Recerca i Estudis Avançais, Barcelona, ES;
Abstract
This study describes a method to determine the likelihood of the development of metastasis in a subject suffering from cancer, in addition to a method to design a customized therapy in a subject suffering from cancer, in particular breast, colon, lung, kidney and thyroid cancer, based on the determination of the expression level of one or more genes whose expression is modulated by an increase in c-MAF expression. It also describes a method for the identification of marker genes with a propensity for metastatic cancer based on inducing the modulation of the c-MAF expression Finally, the use of PTHLH and PODXL inhibitors and RERG activators in the treatment and/or prevention of the cancer, in particular breast, colon, lung, kidney and thyroid cancer.