The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Apr. 16, 2020
Applicant:
General Electric Company, Schenectady, NY (US);
Inventors:
Vasile Bogdan Neculaes, Niskayuna, NY (US);
Andrew Soliz Torres, Niskayuna, NY (US);
Steve Lambert Klopman, Clifton Park, NY (US);
Assignee:
General Electric Company, Schenectady, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 13/00 (2006.01); C12N 5/078 (2010.01); A61K 35/19 (2015.01); A61K 38/18 (2006.01); A61K 33/06 (2006.01); A61K 41/00 (2020.01);
U.S. Cl.
CPC ...
C12N 13/00 (2013.01); A61K 35/19 (2013.01); A61K 38/18 (2013.01); A61K 41/00 (2013.01); C12N 5/0644 (2013.01); A61K 33/06 (2013.01);
Abstract
The present disclosure relates to the generation of an activated platelet product in which one or more of the presence or absence of clots, the timing of clot formation (if present), and/or the mechanical strength of clots (if present) is controlled by the presence or concentration of calcium ions during the activation process. In certain embodiments, the calcium ion concentration is controlled in the presence of pulsed electric fields or a chemical activator (e.g., thrombin) as part of the activation process.