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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11591579 B1

PDFFull Text
Date of Patent:
Feb. 28, 2023

Filed:

Nov. 01, 2021

Human methylthioadenosine/adenosine depleting enzyme variants for cancer therapy

Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventor:

Everett Stone, Austin, TX (US);

Assignee:

BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);

Attorney:

Parker Highlander PLLC

Primary Examiner:

Susan M Hanley

Int. Cl.
CPC ...
C12N 9/10 (2006.01); A61K 47/60 (2017.01); C07K 16/28 (2006.01); A61P 35/00 (2006.01); A61K 38/45 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1077 (2013.01); A61K 38/45 (2013.01); A61K 45/06 (2013.01); A61K 47/60 (2017.08); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); C12Y 204/02028 (2013.01);
Abstract

Disclosed herein are compositions related to conjugated polypeptides with MTA/ADO-degrading enzyme activity. The conjugated polypeptides are engineered to allow for maximal conjugation while maintaining catalytic activities. Also disclosed are nucleic acids, expression vectors, and host cells related to the conjugated polypeptides. Further disclosed are methods of using the pharmaceutical formulations comprising above to treat cancer.

Find Patent Forward Citations

Stone, Everett. (2023). Human methylthioadenosine/adenosine depleting enzyme variants for cancer therapy (U.S. Patent No. 11591579). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11591579

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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