The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Mar. 01, 2017
Applicant:
Koninklijke Nederlandse Akademie Van Wetenschappen, Utrecht, NL;
Inventors:
Johannes Carolus Clevers, Utrecht, NL;
Helmuth Gehart, Utrecht, NL;
Assignee:
Koninklijke Nederlandse Akademie Van Wetenschappen, Utrecht, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61K 35/407 (2015.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0672 (2013.01); A61K 35/407 (2013.01); C12N 5/0671 (2013.01); G01N 33/5088 (2013.01); C12N 2501/01 (2013.01); C12N 2501/11 (2013.01); C12N 2501/119 (2013.01); C12N 2501/12 (2013.01); C12N 2501/155 (2013.01); C12N 2501/345 (2013.01); C12N 2501/39 (2013.01); C12N 2501/415 (2013.01); C12N 2501/42 (2013.01); C12N 2501/727 (2013.01); C12N 2501/805 (2013.01); C12N 2501/999 (2013.01); C12N 2506/14 (2013.01);
Abstract
The invention relates to differentiation methods for progenitor cells, e.g. mammalian epithelial stem cells, differentiation media for use in said methods, organoids and cells obtainable by said methods and uses, including therapeutic uses, thereof.