The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Nov. 24, 2021
Applicant:
Akagera Medicines, Inc., Boxford, MA (US);
Inventors:
Daryl C. Drummond, Lincoln, MA (US);
Dmitri B. Kirpotin, San Francisco, CA (US);
Mark E. Hayes, Mill Valley, CA (US);
Assignee:
Akagera Medicines, Inc., Boxford, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C11C 3/00 (2006.01); C07F 9/09 (2006.01); C07D 317/28 (2006.01);
U.S. Cl.
CPC ...
C11C 3/003 (2013.01); C07D 317/28 (2013.01); C07F 9/091 (2013.01);
Abstract
The present disclosure provides compounds useful as ionizable cationic lipids. The ionizable cationic lipids are useful for preparing lipid nanoparticles for the delivery of therapeutic nucleic acids to cells. Cationic ionizable lipids were engineered with improved stability to oxidative degradation while in storage.