The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Mar. 28, 2018
Applicant:
Beijing Hanmi Pharm. Co., Ltd., Beijing, CN;
Inventors:
Jiawang Liu, Shunyi District, CN;
Nanmeng Song, Shunyi District, CN;
Yaping Yang, Shunyi District, CN;
Mengxie Jin, Shunyi District, CN;
Assignee:
BEIJING HANMI PHARM. CO., LTD., Beijing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/46 (2006.01); C07K 16/30 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/468 (2013.01); C07K 16/30 (2013.01); A61K 38/00 (2013.01); C07K 2317/14 (2013.01); C07K 2317/31 (2013.01); C07K 2317/56 (2013.01);
Abstract
Provided are an anti-PD-L1/anti-PD-1 natural antibody structure-like heterodimeric bispecific antibody and a preparation thereof. In particular, provided are a highly stable heterodimeric anti-PD-L1/anti-PD-1 bispecific antibody with characteristics of a natural IgG and without mismatches heavy chain-light chain, and a preparation thereof. The bispecific antibody can bind to both target molecules and is more effective in treating a complex disease.