The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Nov. 08, 2018
Applicant:
National Research Council of Canada, Ottawa, CA;
Inventors:
Michel Gilbert, Gatineau, CA;
Traian Sulea, Kirkland, CA;
Maria L. Jaramillo, Beaconsfield, CA;
Yves Durocher, Montreal, CA;
Maurizio Acchione, Pierrefonds, CA;
Assignee:
National Research Council of Canada, Ottawa, CA;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/46 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C07K 16/46 (2013.01); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); C07K 2317/24 (2013.01); C07K 2317/41 (2013.01); C07K 2317/55 (2013.01); C12Y 204/99001 (2013.01);
Abstract
The present invention relates to compounds, compositions, and methods are provided for covalently linking a cargo molecule, such as a therapeutic or a diagnostic agent, to a glycan in the Fab region of an antibody. Also provided are methods of modeling and producing antibodies having de novo Fab glycosylation sites. Also provided are antibody carrier conjugates, methods of using the conjugates.