The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

Apr. 23, 2020
Applicants:

Janssen Pharmaceuticals, Inc., Titusville, NJ (US);

Ac Immune SA, Lausanne, CH;

Inventors:

Elizabeth Anne Ramsburg, Chalfont, PA (US);

Donata De Marco, Turnhout, BE;

Chakkumkal Anish, The Hague, NL;

Charlotte Sadaka, San Diego, CA (US);

Jaap Goudsmit, Amsterdam, NL;

Andreas Muhs, Cugy, CH;

Maria Pihlgren Bosch, Mont-Sur-Lausanne, CH;

Marija Vukicevic Verhille, St-Sulpice, CH;

David Hickman, St-Sulpice, CH;

Nicolas Piot, Grandvaux, CH;

Saroj Raj Ghimire, Chavannes-Pres-Renens, CH;

Assignees:

Janssen Pharmaceuticals, Inc., Titusville, NJ (US);

AC Immune SA, Lausanne, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 39/00 (2006.01); A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4711 (2013.01); A61K 9/1271 (2013.01); A61K 39/0007 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55572 (2013.01); A61K 2039/6018 (2013.01); A61K 2039/627 (2013.01);
Abstract

Methods for inducing an immune response against tau protein in a subject suffering from a neurodegenerative disease, disorder or condition, such as Alzheimer's Disease, are described. The methods include administering a liposomal priming composition containing tau peptides, preferably phosphorylated tau peptides, and a conjugate boosting composition containing tau peptides, preferably phosphorylated tau peptides, conjugated to an immunogenic carrier.


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