The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

Aug. 13, 2020
Applicant:

Vertex Pharmaceuticals Incorporated, Boston, MA (US);

Inventors:

Corey Don Anderson, Brighton, MA (US);

Jeremy J. Clemens, San Diego, CA (US);

Thomas Cleveland, San Marcos, CA (US);

Timothy Richard Coon, Carlsbad, CA (US);

Bryan Frieman, La Jolla, CA (US);

Peter Grootenhuis, Del Mar, CA (US);

Sara Sabina Hadida Ruah, La Jolla, CA (US);

Jason McCartney, Cardiff by the Sea, CA (US);

Mark Thomas Miller, San Diego, CA (US);

Prasuna Paraselli, San Diego, CA (US);

Fabrice Pierre, La Jolla, CA (US);

Sara E. Swift, San Diego, CA (US);

Jinglan Zhou, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 7/30 (2006.01); C07F 7/08 (2006.01); A61K 31/404 (2006.01); A61K 31/47 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07F 7/0816 (2013.01); A61K 31/404 (2013.01); A61K 31/47 (2013.01); C07F 7/30 (2013.01); A61K 45/06 (2013.01); C07B 2200/05 (2013.01);
Abstract

This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, and processes for making such modulators.


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