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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11591334 B1

PDFFull Text
Date of Patent:
Feb. 28, 2023

Filed:

May. 04, 2018

Substituted pyrrolizines for the treatment of hepatitis b

Applicant:

Shanghai Longwood Biopharmaceuticals Co., Ltd., Shanghai, CN;

Inventors:

Zhe Wang, Shanghai, CN;

Guoqin Fan, Shanghai, CN;

Cenbin Lu, Shanghai, CN;

Sai Yang, Shanghai, CN;

Xiaoguang Wang, Shanghai, CN;

Assignee:

SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD., Shanghai, CN;

Attorney:

Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
A61K 31/167 (2006.01); C07C 233/57 (2006.01); C07D 487/04 (2006.01); A61P 31/20 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 31/20 (2018.01); C07D 471/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to a bicyclic nucleocapsid inhibitor and the use of the same as a drug in the treatment of hepatitis B. In particular, disclosed is a compound having a structure shown by the following formula (A1): or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt, a hydrate, or a solvate thereof, that can be used as an HBV inhibitor, wherein the definition of each group is as described in detail in the description. The present invention also relates to a pharmaceutical composition comprising the compound and the use of the same in the treatment of hepatitis B.

Find Patent Forward Citations

Wang, Zhe. (2023). Substituted pyrrolizines for the treatment of hepatitis b (U.S. Patent No. 11591334). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11591334

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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