The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Aug. 04, 2020
Applicant:
Albert Einstein College of Medicine, Bronx, NY (US);
Inventors:
Ana Maria Cuervo, Bronx, NY (US);
Evripidis Gavathiotis, Flushing, NY (US);
Qisheng Xin, Bronx, NY (US);
Bhaskar C. Das, Kansas City, KS (US);
Assignee:
ALBERT EINSTEIN COLLEGE OF MEDICINE, INC., Bronx, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/10 (2006.01); C07D 265/36 (2006.01); C07C 279/22 (2006.01);
U.S. Cl.
CPC ...
C07D 413/10 (2013.01); C07C 279/22 (2013.01); C07D 265/36 (2013.01); C07B 2200/11 (2013.01); C07C 2601/16 (2017.05); G01N 2500/04 (2013.01); G01N 2800/7009 (2013.01);
Abstract
Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RARα) in subjects in need thereof.