The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

Apr. 08, 2020
Applicants:

Tohoku University, Sendai, JP;

Junsei Educational Institution, Okayama, JP;

Fuso Pharmaceutical Industries, Ltd., Osaka, JP;

Inventors:

Haruhisa Kikuchi, Tokyo, JP;

Yoshiteru Oshima, Sendai, JP;

Toshio Hattori, Takahashi, JP;

Osamu Yamada, Osaka, JP;

Jing Zhang, Osaka, JP;

Shinya Kida, Osaka, JP;

Shinya Murase, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/60 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 211/60 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R, R, m and n are as defined in the specification, with an inhibitory effect of PD-L1 expression and an inhibitory effect of reduced production of IL-2 and a medicament useful for the treatment of a disease associated with the reduced immune function caused by the formation of PD-1/PD-L1 binding.


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