The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

Oct. 22, 2019
Applicant:

Battelle Memorial Institute, Columbus, OH (US);

Inventors:

Eric C. Scribben, Springfield, OH (US);

Steven M. Risser, Reynoldsburg, OH (US);

Amy M. Heintz, Dublin, OH (US);

Jeffrey L. Ellis, Gahanna, OH (US);

John D. Clay, Gahanna, OH (US);

Timothy M. Blum, Columbus, OH (US);

Assignee:

Battelle Memorial Institute, Columbus, OH (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61M 5/20 (2006.01); A61M 5/19 (2006.01); A61M 5/28 (2006.01); A61M 5/24 (2006.01); A61M 5/31 (2006.01); A61M 5/315 (2006.01);
U.S. Cl.
CPC ...
A61M 5/20 (2013.01); A61M 5/19 (2013.01); A61M 5/284 (2013.01); A61M 5/286 (2013.01); A61M 5/204 (2013.01); A61M 5/2448 (2013.01); A61M 5/2459 (2013.01); A61M 5/3134 (2013.01); A61M 5/31596 (2013.01); A61M 2005/247 (2013.01); A61M 2005/3128 (2013.01); A61M 2005/31598 (2013.01); A61M 2202/07 (2013.01); A61M 2206/18 (2013.01);
Abstract

Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.


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