The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

May. 14, 2018
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Shuai Shi, Whippany, NJ (US);

Valentyn Antochshuk, Cranford, NJ (US);

Inventors:

Shuai Shi, Whippany, NJ (US);

Valentyn Antochshuk, Cranford, NJ (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/28 (2006.01); A61K 47/64 (2017.01); A61P 3/10 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 38/26 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
A61K 47/64 (2017.08); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 38/26 (2013.01); A61K 38/28 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/183 (2013.01); A61P 3/10 (2018.01);
Abstract

This disclosure relates to stable aqueous pharmaceutical formulations comprising a therapeutically effective amount of an incretin-insulin conjugate as well as methods of using the same, and aqueous pharmaceutical formulations containing an incretin-insulin conjugate which are stable and which provide a protracted pharmacodynamics profile, which include L-arginine HCl and phenol (or m-cresol) as stabilizing agents. The invention also provide a method of treating a patient or individual having a metabolic disease, comprising administering to the patient or individual an effective amount of any of the aqueous pharmaceutical formulations described herein.


Find Patent Forward Citations

Shi, Shuai. (2023). Pharmaceutical formulation comprising incretin-insulin conjugates (U.S. Patent No. 11590237). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11590237

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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