The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Sep. 29, 2017
Applicant:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Inventors:
Peter X. Ma, Ann Arbor, MI (US);
Xiaojin Zhang, Wuhan, CN;
Assignee:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/00 (2006.01); A61K 47/50 (2017.01); A61K 47/59 (2017.01); C08G 83/00 (2006.01); C08G 73/02 (2006.01); C08F 210/02 (2006.01); C08G 63/66 (2006.01); A61K 47/69 (2017.01); A61K 47/60 (2017.01); A61L 27/18 (2006.01); A61L 27/26 (2006.01); A61L 27/44 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); C08G 81/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/593 (2017.08); A61K 47/50 (2017.08); A61K 47/60 (2017.08); A61K 47/6937 (2017.08); A61L 27/18 (2013.01); A61L 27/26 (2013.01); A61L 27/44 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); C08F 210/02 (2013.01); C08G 63/66 (2013.01); C08G 73/024 (2013.01); C08G 73/0206 (2013.01); C08G 81/00 (2013.01); C08G 83/00 (2013.01); C08G 83/005 (2013.01); C12N 15/113 (2013.01); A61L 2300/258 (2013.01); A61L 2300/604 (2013.01); A61L 2430/02 (2013.01); C08G 2210/00 (2013.01); C08G 2230/00 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/351 (2013.01); C12N 2310/51 (2013.01); C12N 2310/52 (2013.01);
Abstract
A hyperbranched polymer includes a hyperbranched, hydrophobic molecular core, respective low molecular weight polyethyleneimine chains attached to at least three branches of the hyperbranched, hydrophobic molecular core, and respective polyethylene glycol chains attached to at least two other branches of the hyperbranched, hydrophobic molecular core. Examples of the hyperbranched polymer may be used to form hyperbranched polyplexes, and may be included in DNA or RNA delivery systems.