The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Oct. 06, 2017
Applicant:
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Inventors:
William R. Wagner, Gibsonia, PA (US);
Yasumoto Matsumura, Pittsburgh, PA (US);
Murugesan Velayutham, Pittsburgh, PA (US);
Yang Zhu, Pittsburgh, PA (US);
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/74 (2006.01); A61K 31/79 (2006.01); A61K 9/00 (2006.01); C08F 290/06 (2006.01); A61L 31/14 (2006.01); C08F 220/54 (2006.01); C08F 299/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/79 (2013.01); A61K 9/0019 (2013.01); A61K 9/0024 (2013.01); A61L 31/145 (2013.01); C08F 220/54 (2013.01); C08F 290/061 (2013.01); C08F 299/045 (2013.01); A61L 2400/06 (2013.01); C08F 2438/02 (2013.01);
Abstract
Provided herein are antioxidant, thermally-responsive copolymer-based compositions and methods of making and using the compositions, e.g., for treatment of ischemia reperfusion injury in a patient. The copolymer comprises a hydrocarbyl backbone, and a plurality of pendant pyrrolidone, antioxidant radical, polyester oligomer, and N-alkyl amide groups.