The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

Nov. 05, 2018
Applicant:

Industry-academic Cooperation Foundation, Yonsei University, Seoul, KR;

Inventors:

Beom Seok Kim, Seoul, KR;

Chui Hoon Kim, Gyeonggi-do, KR;

Jong Jin Yoon, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/683 (2006.01); A61K 31/137 (2006.01); A61K 31/191 (2006.01); A61K 31/357 (2006.01); A61K 31/496 (2006.01); A61K 31/397 (2006.01); A61K 31/4418 (2006.01); A61K 31/445 (2006.01);
U.S. Cl.
CPC ...
A61K 31/683 (2013.01); A61K 31/137 (2013.01); A61K 31/191 (2013.01); A61K 31/357 (2013.01); A61K 31/496 (2013.01); A61K 31/397 (2013.01); A61K 31/445 (2013.01); A61K 31/4418 (2013.01);
Abstract

The present disclosure relates to a pharmaceutical composition for preventing or treating statin-induced adverse effects or a pharmaceutical composition for co-administration with statin, the pharmaceutical composition containing, as an active ingredient, at least one selected from the group consisting of an isoprenoid-based compound, zaragozic acid, terbinafine, and ketoconazole. The pharmaceutical composition according to the present disclosure may prevent and/or treat adverse statin effects that can be induced by statin, that is, can be induced at any time by oxisterols present at abnormal levels in the body. The pharmaceutical composition can not only treat but also prevent the adverse effects of various statin therapeutics whose use has recently increased rapidly, and thus it is expected that the pharmaceutical composition can be widely used for various diseases and the utilization thereof can further be increased.


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