The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

Nov. 28, 2017
Applicant:

Pharma Mar, S.a., Madrid, ES;

Assignee:

PHARMA MAR, S.A., Madrid, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4995 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61K 31/69 (2006.01); A61K 31/7068 (2006.01); A61K 45/06 (2006.01); A61K 38/15 (2006.01); A61K 33/243 (2019.01); A61K 31/337 (2006.01); A61K 31/4164 (2006.01); A61K 31/4188 (2006.01); A61K 31/4375 (2006.01); A61K 31/55 (2006.01); A61K 31/704 (2006.01); A61P 11/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4995 (2013.01); A61K 31/337 (2013.01); A61K 31/4164 (2013.01); A61K 31/4188 (2013.01); A61K 31/4375 (2013.01); A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61K 31/55 (2013.01); A61K 31/69 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 33/243 (2019.01); A61K 38/15 (2013.01); A61K 45/06 (2013.01); A61P 11/00 (2018.01); A61P 35/00 (2018.01);
Abstract

The present invention relates to the combination of PM01183 with several anticancer drugs, in particular other anticancer drugs selected from antitumor platinum coordination complexes, antimetabolites, mitotic inhibitors, anticancer antibiotics, topoisomerase I and/or II inhibitors, proteasome inhibitors, histone deacetylase inhibitors, nitrogen mustard alkylating agents, nitrosourea alkylating agents, nonclassical alkylating agents, estrogen antagonists, androgen antagonists, mTOR inhibitors, tyrosine kinase inhibitors, and other agents selected from aplidine, ET-743, PM02734 and PM00104, and the use of these combinations in the treatment of cancer.


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