The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

Sep. 25, 2019
Applicant:

Hisamitsu Pharmaceutical Co., Inc., Tosu, JP;

Inventors:

Masaki Yukuhiro, Tsukuba, JP;

Yuka Takagi, Tsukuba, JP;

Yasunari Michinaka, Tsukuba, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/407 (2006.01); A61K 9/70 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/32 (2006.01);
U.S. Cl.
CPC ...
A61K 31/407 (2013.01); A61K 9/7069 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/32 (2013.01);
Abstract

An object of the present invention is to provide an asenapine-containing patch having excellent sustained-release properties while enhancing skin permeability by using a silicone-based pressure-sensitive adhesive base. The present invention relates to a patch having a support and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer comprises asenapine and/or a pharmaceutically acceptable salt thereof, a silicone-based pressure-sensitive adhesive base and a release control agent, and the ratio of the maximum skin permeation rate of asenapine to the minimum skin permeation rate from the time when the maximum skin permeation rate is reached to 24 hours is less than 1.62.


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