The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2023
Filed:
Feb. 25, 2021
Applicant:
Purdue Pharma L.p., Stamford, CT (US);
Inventor:
Haiyong Hugh Huang, Princeton, NJ (US);
Assignee:
Purdue Pharma L.P., Stamford, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 9/24 (2006.01); A61K 31/485 (2006.01); A61K 9/00 (2006.01); A61K 9/28 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2077 (2013.01); A61K 9/0053 (2013.01); A61K 9/209 (2013.01); A61K 9/2031 (2013.01); A61K 9/2054 (2013.01); A61K 9/2086 (2013.01); A61K 9/28 (2013.01); A61K 31/485 (2013.01);
Abstract
In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a core comprising a first portion of an opioid analgesic dispersed in a first matrix material; and a shell encasing the core and comprising a second portion of the opioid analgesic dispersed in a second matrix material; wherein the amount of opioid analgesic released from the dosage form is proportional within 20% to elapsed time from 8 to 24 hours, as measured by an in-vitro dissolution in a USP Apparatus 1 (basket) at 100 rpm in 900 ml simulated gastric fluid without enzymes (SGF) at 37 C.