The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2023

Filed:

Jun. 26, 2020
Applicant:

C.r. Bard, Inc., Tempe, AZ (US);

Inventors:

Elena Afonina, Franklin Lakes, NJ (US);

Hiep Do, Franklin Lakes, NJ (US);

Emily Goel, Franklin Lakes, NJ (US);

Oleg Guryev, Franklin Lakes, NJ (US);

Cyal Lecy, Franklin Lakes, NJ (US);

Majid Mehrpouyan, Franklin Lakes, NJ (US);

Michael Randall, Franklin Lakes, NJ (US);

Marybeth Sharkey, Franklin Lakes, NJ (US);

Jeffrey Wang, Franklin Lakes, NJ (US);

Assignee:

C.R. Bard, Inc., Franklin Lakes, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 31/4412 (2006.01); A61K 9/19 (2006.01); A61K 9/14 (2006.01); A61K 9/127 (2006.01); A61K 31/704 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1652 (2013.01); A61K 9/127 (2013.01); A61K 9/146 (2013.01); A61K 9/19 (2013.01); A61K 31/4412 (2013.01); A61K 31/704 (2013.01);
Abstract

Drug-loaded microbead compositions include microbeads of a biodegradable material and vesicular agents located within or associated with the biodegradable material of the microbeads. The vesicular agents include a lipid bilayer and comprise liposomes or ethosomes. The drug-loaded microbeads include a first therapeutic agent associated with the vesicular agents, and a second therapeutic agent different from the first therapeutic agent. The vesicular agents include a lipid bilayer surrounding a vesicular core. The second therapeutic agent is contained within the microbeads or associated with the microbeads through ionic or non-covalent interaction and may or may not be associated with the vesicular agents. Drug-loaded biodegradable microbead compositions include microbeads of biodegradable material and a therapeutic agent.


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