The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
Mar. 29, 2022
Bostongene Corporation, Waltham, MA (US);
Aleksandr Zaitsev, Drozhzhino, RU;
Maksim Chelushkin, Moscow, RU;
Ilya Cheremushkin, Moscow, RU;
Ekaterina Nuzhdina, Moscow, RU;
Vladimir Zyrin, Moscow, RU;
Daniiar Dyikanov, Moscow, RU;
Alexander Bagaev, Moscow, RU;
Ravshan Ataullakhanov, Moscow, RU;
Boris Shpak, Krasnoyarsk, RU;
BostonGene Corporation, Waltham, MA (US);
Abstract
Techniques for determining one or more cell composition percentages from expression data. The techniques include obtaining expression data for a biological sample, the biological sample previously obtained from a subject, the expression data including first expression data associated with a first set of genes associated with a first cell type; determining a first cell composition percentage for the first cell type using the expression data and one or more non-linear regression models including a first non-linear regression model, wherein the first cell composition percentage indicates an estimated percentage of cells of the first cell type in the biological sample, wherein determining the first cell composition percentage for the first cell type comprises: processing the first expression data with the first non-linear regression model to determine the first cell composition percentage for the first cell type; and outputting the first cell composition percentage.