The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2023

Filed:

Apr. 09, 2019
Applicant:

Mars Sciences Limited, Grand Cayman, KY;

Inventors:

Ronald T. Laborde, San Diego, CA (US);

Yu Ge, San Diego, CA (US);

Kevin N. Walda, San Diego, CA (US);

Assignee:

Mars Sciences Limited, George Town, KY;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01R 33/56 (2006.01); G01N 33/543 (2006.01); G01R 33/07 (2006.01); A61K 49/18 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01R 33/5601 (2013.01); A61K 49/1878 (2013.01); G01N 33/587 (2013.01); G01R 33/07 (2013.01); G01N 33/54326 (2013.01);
Abstract

Superparamagnetic nanoparticle-based analytical method comprising providing a sample having analytes in a sample matrix, providing a point of care chip having analytical regions, each of which is a stationary phase having at least one or more sections, labeling each of the analytes with a superparamagnetic nanoparticle and immobilizing the labeled analytes in the stationary phase, providing an analytical device having a means for exciting the superparamagnetic nanoparticles in vitro and a means for sensing, receiving, and transmitting response of the excited superparamagnetic nanoparticles, placing the chip in the analytical device and exciting the superparamagnetic nanoparticles in vitro, sensing, receiving, and transmitting the response of the superparamagnetic nanoparticles, and analyzing the response and determining characteristic of the analytes, wherein the response of the superparamagnetic nanoparticles comprises harmonics. The present invention also provides the hybrid point of care chip and analyzer to be used in the analytical method.


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