The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
Oct. 16, 2015
Children's Hospital Medical Center, Cincinnati, OH (US);
James M. Wells, Cincinnati, OH (US);
Carey Lane Watson, Cincinnati, OH (US);
Jorge Orlando Munera, Cincinnati, OH (US);
Maxime Mickael Mahe, Cincinnati, OH (US);
Michael A. Helmrath, Cincinnati, OH (US);
Michael J. Workman, Santa Monica, CA (US);
Children's Hospital Medical Center, Cincinnati, OH (US);
Abstract
Disclosed are methods for making a vascularized hollow organ derived from human intestinal organoid (HIOs). The HIOs may be obtained from human embryonic stem cells (ESC's) and/or induced pluripotent stem cells (iPSCs), such that the HIO forms mature intestinal tissue. Also disclosed are methods for making a human intestinal tissue containing a functional enteric nervous system (ENS).