The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2023

Filed:

Sep. 28, 2015
Applicant:

Koligo Therapeutics, Inc., New Albany, IN (US);

Inventors:

Gregory D. Ariff, Herndon, VA (US);

Thomas Cannon, Honolulu, HI (US);

Jennifer L. Case, Alexandria, VA (US);

Christian L. Haller, Alexandria, VA (US);

Paul Kosnik, Honolulu, HI (US);

Charles P. Luddy, Alexandria, VA (US);

Craig A. Mauch, Clifton Park, NY (US);

Erik Vossman, Honolulu, HI (US);

Stuart K. Williams, Tucson, AZ (US);

Assignee:

TISSUE GENESIS, INC, Honolulu, HI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12M 47/04 (2013.01); A61K 35/12 (2013.01); C12M 45/05 (2013.01); C12M 45/06 (2013.01); C12M 45/09 (2013.01);
Abstract

The present invention provides automated devices for use in supporting various cell therapies and tissue engineering methods. The present invention provides an automated cell separation apparatus capable of separating cells from a tissue sample for use in cell therapies and/or tissue engineering. The cell separation apparatus can be used in combination with complementary devices such as cell collection device and/or a sodding apparatus to support various therapies. The automated apparatus includes media and tissue dissociating chemical reservoirs, filters, a cell separator and a perfusion flow loop through a graft chamber which supports a graft substrate or other endovascular device. The present invention further provides methods for using the tissue grafts and cell samples prepared by the devices described herein in a multitude of therapies including revascularization, regeneration and reconstruction of tissues and organs, as well as treatment and prevention of diseases.


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