The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
May. 04, 2020
Applicant:
Absci, Llc, Vancouver, WA (US);
Inventors:
Amy Doerner, Vancouver, WA (US);
Michael Cammarata, Vancouver, WA (US);
Tyler Nusca, Portland, OR (US);
Suzanne A. Sprunger, Port Ludlow, WA (US);
Melissa Patterson, Portland, OR (US);
Assignee:
ABSCI, LLC, Vancouver, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 14/62 (2006.01); C12N 9/48 (2006.01); C12N 9/96 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); C07K 14/62 (2013.01); C12N 9/485 (2013.01); C12N 9/96 (2013.01); C12Y 304/17002 (2013.01); C07K 2319/00 (2013.01);
Abstract
A connecting polypeptide has SEQ ID NO:73. A proinsulin polypeptide includes a mature insulin A-chain, a mature insulin B-chain, and a connecting peptide comprising SEQ ID NO: 73 linking the mature A-chain and the mature B-chain, wherein the connecting peptide is not a native human proinsulin C-peptide. The proinsulin polypeptides according to the invention can be made in high titers and in high purity.