The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
Sep. 23, 2016
Reata Pharmaceuticals, Inc., Irving, TX (US);
Melean Visnick, Irving, TX (US);
Xin Jiang, Coppell, TX (US);
Martha R. Hotema, Hurst, TX (US);
Chitase Lee, Ann Arbor, MI (US);
Bradley William Caprathe, Livonia, MI (US);
William H. Roark, Ann Arbor, MI (US);
Gary L. Bolton, Ann Arbor, MI (US);
REATA PHARMACEUTICALS, Inc., Irving, TX (US);
Abstract
Disclosed herein are C4 modified oleanolic acid derivatives of the formula: Formula (X) or Formula (XII), as well as analogs thereof, wherein the variables are defined herein. In addition, disclosed herein are pharmaceutical compositions of these derivatives or analogs, methods for their manufacture, and methods for their use, including for the prevention and treatment of diseases or disorders associated with overproduction of IL-17.