The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
May. 28, 2020
Applicant:
Ecstasy Llc, Chapel Hill, NC (US);
Inventors:
Xiaodong Wang, Chapel Hill, NC (US);
Hua Zhong, Acton, MA (US);
Assignee:
ECSTASY LLC, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 205/04 (2006.01); C07D 409/04 (2006.01); C07D 211/12 (2006.01); C07D 211/34 (2006.01); C07D 223/04 (2006.01); C07D 223/06 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07F 5/02 (2006.01); C07D 475/00 (2006.01); C07D 211/14 (2006.01); C07D 207/09 (2006.01); C07D 417/06 (2006.01); C07D 417/10 (2006.01); C07D 409/06 (2006.01); C07D 451/02 (2006.01); C07D 473/00 (2006.01); C07D 471/08 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); C07D 205/04 (2013.01); C07D 207/09 (2013.01); C07D 211/14 (2013.01); C07D 211/34 (2013.01); C07D 223/04 (2013.01); C07D 223/06 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 409/06 (2013.01); C07D 409/14 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/10 (2013.01); C07D 417/14 (2013.01); C07D 451/02 (2013.01); C07D 471/08 (2013.01); C07D 473/00 (2013.01); C07D 475/00 (2013.01); C07D 513/04 (2013.01);
Abstract
The present invention provides a genus of polycyclic amines that are useful as opioid receptor modulators. The compounds of the invention are useful in both therapeutic and diagnostic methods, including for treating pain, neurological disorders, cardiac disorders, bowel disorders, drug and alcohol addiction, drug overdose, urinary disorders, respiratory disorders, sexual dysfunction, psoriasis, graft rejection or cancer.