The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
Oct. 16, 2020
Applicant:
C4 Therapeutics, Inc., Watertown, MA (US);
Inventors:
Christopher G. Nasveschuk, Stoneham, MA (US);
Fabian Dey, Basel, CH;
Annick Goergler, Basel, CH;
Bernd Kuhn, Reinach BL, CH;
Roger Norcross, Basel, CH;
Stephan Roever, Basel, CH;
Philipp Schmid, Basel, CH;
Assignee:
C4 Therapeutics, Inc., Watertown, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/10 (2006.01); A61K 31/438 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/10 (2013.01); C07D 519/00 (2013.01);
Abstract
The present invention provides compounds which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and their use for the treatment of abnormal cellular proliferation. The present invention also provides compounds that may be used as synthetic intermediates in the synthesis of bifunctional compounds used for targeted protein degradation.