The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
Feb. 20, 2019
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Nathanael S. Gray, Jamaica Plain, MA (US);
Dries De Clercq, Boston, MA (US);
Jaebong Jang, Boston, MA (US);
Pasi Janne, Needham, MA (US);
Ciric To, Boston, MA (US);
Michael Eck, Boston, MA (US);
Eunyoung Park, Boston, MA (US);
David Heppner, Boston, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 243/38 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 243/38 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 417/14 (2013.01);
Abstract
The application relates to a compound having Formula Ia or Ib: or a pharmaceutically acceptable salt, hydrate, or solvate thereof, which modulates the activity of EGFR, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which EGFR plays a role.