The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2023

Filed:

Aug. 13, 2019
Applicants:

Shanghai Jingxin Biology & Pharmaceutical Co., Ltd, Shanghai, CN;

Zhejiang Jingxin Pharmaceutical Co., Ltd., Zhejiang, CN;

Inventors:

Yue Huang, Zhejiang, CN;

Fei Zheng, Zhejiang, CN;

Xiaoyun Fu, Zhejiang, CN;

Chunlan Tang, Zhejiang, CN;

Dan Zhu, Zhejiang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/66 (2006.01); A61K 31/496 (2006.01); C07D 409/04 (2006.01);
U.S. Cl.
CPC ...
C07D 333/66 (2013.01); A61K 31/496 (2013.01); C07D 409/04 (2013.01);
Abstract

The present invention provides a maleate, phosphate, sulfate, hydrochloride of a cyclohexane derivative, N'-[trans-4-[2-[7-(benzo[b]thiophene)-7-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, as shown in Formula I and crystal forms thereof. The crystal forms have low hygroscopicity and good stability and are convenient for long-term storage and transportation; or the crystal forms have a long half-life in vivo, high bioavailability and small individual difference, and thus have obvious clinical application advantages.


Find Patent Forward Citations

Loading…