The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2023

Filed:

Oct. 02, 2020
Applicant:

Stealth Biotherapeutics Inc., Needham, MA (US);

Inventors:

Dennis Keefe, Bedford, MA (US);

Guozhu Zheng, Lexington, MA (US);

Pavels Arsenjans, Riga, LV;

Assignee:

STEALTH BIOTHERAPEUTICS INC., Needham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 49/835 (2006.01); C07D 305/10 (2006.01);
U.S. Cl.
CPC ...
C07D 305/10 (2013.01); C07C 49/835 (2013.01);
Abstract

The disclosure provides therapeutic compositions (i.e., therapeutic agents) and methods of preventing or treating Friedreich's ataxia in a mammalian subject, reducing risk factors, signs and/or symptoms associated with Friedreich's ataxia (e.g., Complex I deficiency), and/or reducing the likelihood or severity of Friedreich's ataxia. The disclosure further provides novel intermediates for the production of said therapeutic compositions and related reduced versions of said therapeutic compositions, which reduce forms may also be used as therapeutic agents (or prodrugs of the therapeutic agent(s)).


Find Patent Forward Citations

Loading…