The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2023

Filed:

Mar. 12, 2020
Applicants:

Duke University, Durham, NC (US);

Unm Rainforest Innovations, Albuquerque, NM (US);

Inventors:

Gabriel P. Lopez, Durham, NC (US);

Joseph R. Simon, Durham, NC (US);

Nick J. Carroll, Durham, NC (US);

Ashutosh Chilkoti, Durham, NC (US);

Assignees:

UNM Rainforest Innovations, Albuquerque, NM (US);

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); B01J 2/00 (2006.01); C07K 14/78 (2006.01); A61L 31/16 (2006.01); A61L 27/34 (2006.01); A61L 29/08 (2006.01); A61L 31/10 (2006.01); C12M 1/00 (2006.01); B01J 13/06 (2006.01); C07K 19/00 (2006.01); A61K 38/00 (2006.01); B01J 2/06 (2006.01); A61L 27/54 (2006.01);
U.S. Cl.
CPC ...
B01J 13/06 (2013.01); A61K 9/146 (2013.01); A61K 38/00 (2013.01); A61L 27/34 (2013.01); A61L 27/54 (2013.01); A61L 29/085 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); B01J 2/00 (2013.01); B01J 2/06 (2013.01); C07K 14/78 (2013.01); C07K 19/00 (2013.01); C12M 23/20 (2013.01); A61L 2300/62 (2013.01);
Abstract

Nano- to microscale liquid coacervate particles are provided. The liquid coacervate particles are produced by a process including stimulating a population of liquid droplets containing one or a mixture of components to induce a phase separation point of a first component, and maintaining stimulation at the phase separation point to form a coacervate domain of the first component within each of the droplets to form the liquid coacervate particles. The self-assembled nano, meso, micro and macro liquid coacervate particles and related coated substrates can have utility in drug delivery, bioanalytical systems, controlled cell culture, tissue engineering, biomanufacturing and drug discovery.


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