The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
May. 04, 2018
Applicant:
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Inventors:
Brian H. Santich, New York, NY (US);
Mahiuddin Ahmed, New York, NY (US);
Nai-Kong V. Cheung, New York, NY (US);
Assignee:
Memorial Sloan Kettering Cancer Center, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); A61K 47/54 (2017.01); A61K 51/04 (2006.01); A61K 51/10 (2006.01); C07K 14/47 (2006.01); C07K 14/715 (2006.01); C07K 16/30 (2006.01); C07K 16/44 (2006.01);
U.S. Cl.
CPC ...
A61K 47/641 (2017.08); A61K 47/547 (2017.08); A61K 51/0495 (2013.01); A61K 51/10 (2013.01); A61K 51/1096 (2013.01); C07K 14/4746 (2013.01); C07K 14/7155 (2013.01); C07K 16/3084 (2013.01); C07K 16/44 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/70 (2013.01);
Abstract
The present invention relates to compositions and methods employing conjugates that include a self-assembly and disassembly (SADA) polypeptide and a binding domain. The present invention encompasses the recognition that conjugates with a SADA polypeptide have certain improved biological properties. SADA-conjugates are described, along with uses thereof (e.g., as therapeutic or diagnostic agents) and methods of manufacture.