The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
Sep. 05, 2017
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Christian Klein, Bonstetten, CH;
Hanying Li, Madison, WI (US);
Victor Lyamichev, Madison, WI (US);
Ekkehard Moessner, Kreuzlingen, CH;
Jigar Patel, Verona, WI (US);
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Abstract
The disclosure provides compositions comprising at least one assembly comprising a peptide and a major histocompatibility complex (MHC), wherein the peptide is an integral component of the MHC, wherein the peptide is attached to a surface at its C-terminus through a linker and wherein the peptide is synthesized on the surface. In certain embodiments, the compositions comprise a plurality of assemblies in a spatially-ordered array. The disclosure provides methods for making and using these compositions.