The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2023
Filed:
Dec. 18, 2019
Applicant:
Janssen Pharmaceutica NV, Beerse, BE;
Inventors:
Virginie Sophie Poncelet, Le Manoir sur Seine, FR;
Sophie Coupa, Belbeuf, FR;
Pierre-Henri Storck, Kent, GB;
Bruno Schoentjes, Bois-Guillaume, FR;
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/438 (2006.01); A61K 31/55 (2006.01); A61K 9/28 (2006.01); A61K 45/06 (2006.01); C07D 401/12 (2006.01); C07D 487/04 (2006.01); A61K 31/4439 (2006.01); A61K 31/4709 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 9/28 (2013.01); A61K 31/438 (2013.01); A61K 31/4709 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07D 401/12 (2013.01); C07D 487/04 (2013.01);
Abstract
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds: wherein n, m, p, s, t, R, R, R, R, R, R, R, R, X, Y, Q and Z have defined meanings.