The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2023

Filed:

Jul. 24, 2017
Applicant:

Synaptive Medical Inc., Toronto, CA;

Inventor:

Kresmir Franjic, Toronto, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/055 (2006.01); G01R 33/48 (2006.01); G01R 33/56 (2006.01); A61B 90/00 (2016.01); A61K 49/00 (2006.01); A61K 49/10 (2006.01); H01J 49/04 (2006.01); H01J 49/16 (2006.01); G01N 30/72 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0035 (2013.01); A61B 5/0075 (2013.01); A61B 5/055 (2013.01); A61K 49/0002 (2013.01); A61K 49/103 (2013.01); A61K 49/106 (2013.01); G01N 30/72 (2013.01); G01R 33/4808 (2013.01); G01R 33/5601 (2013.01); H01J 49/0463 (2013.01); H01J 49/168 (2013.01); A61B 2090/397 (2016.02); A61B 2576/00 (2013.01);
Abstract

Disclosed herein is a method for multimodal imaging during a medical procedure using magnetic resonance imaging (MRI) and Raman optical imaging which involves administering an MRI imaging contrast agent that a chemical structure having charge-transfer electronic transitions. The tissue is imaged using and MRI device and the tissue is illuminated with excitation light that has spectral components that are approximately tuned close to one of the charge-transfer electronic transitions thereby producing enhanced Raman optical signals which are analyzed to produce Raman imaging data followed by registering the MRI and Raman imaging data. The present disclosure also provides a method for ionizing laser plumes through atmospheric pressure chemical ionization.


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