The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
Mar. 31, 2017
Applicant:
The Rockefeller University, New York, NY (US);
Inventors:
Assignee:
The Rockefeller University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 14/47 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); C07K 14/47 (2013.01); G01N 21/6428 (2013.01); G01N 2021/6439 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01);
Abstract
The present invention provides methods and compositions relating to an assay for hERG channel protein sensitivity to small molecule pharmacological agents. In one embodiment, the invention includes an engineered hERG channel protein. In another embodiment, the invention includes a method of identifying small molecule pharmacological agents that interfere with repolarization of cardiac cells.