The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2023

Filed:

Mar. 10, 2017
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

The General Hospital Corporation, Boston, MA (US);

Inventors:

Moungi G. Bawendi, Cambridge, MA (US);

Oliver Thomas Bruns, Garching, DE;

Jessica Ann Carr, Cambridge, MA (US);

Klaus van Leyen, Medford, MA (US);

Yi Zheng, Cambridge, MA (US);

Marianne Aellen, Schüpfen, CH;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6456 (2013.01); A61B 5/0071 (2013.01); G01N 21/6428 (2013.01); A61B 2503/40 (2013.01); G01N 2021/6439 (2013.01);
Abstract

Systems and methods for measuring short wave infrared fluorescence and autofluorescent signals are disclosed. In some embodiments, for example, a method may include exposing a portion of tissue that does not include a fluorescent probe to an excitation source of the tissue, wherein at least a portion of the tissue has an autofluorescence spectrum which includes wavelengths greater than 900 nm, and imaging the tissue with a detector that is sensitive to electromagnetic radiation with wavelengths greater than or equal to 900 nm. In certain other embodiments, a system comprises a fluorescent probe including a fluorescent component attached to a carrier, an excitation source, and a detector that detects a tail portion of the fluorescence of the fluorescent component. Methods associated with such a system are also disclosed.


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