The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
Aug. 21, 2017
Applicants:
Adagene Inc., Grand Cayman, KY;
Peter Peizhi Luo, Suzhou, CN;
Inventors:
Assignee:
Adagene Inc., Grand Cayman, KY;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/08 (2006.01); C07K 16/00 (2006.01); C40B 50/04 (2006.01);
U.S. Cl.
CPC ...
C40B 40/08 (2013.01); C07K 16/00 (2013.01); C40B 50/04 (2013.01); C07K 2317/51 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01);
Abstract
Provided herein are libraries containing polynucleotides, where one of the polynucleotides encodes an antibody heavy chain with specific hypervariable regions HVR-H1 and HVR-H2. Further provided herein are libraries containing polynucleotides encoding a plurality of unique antibodies, wherein each antibody comprises a heavy chain variable region and a light chain variable region. Also provided are antibodies, polypeptide libraries, vector libraries, cells, non-human animals, antibody heavy chains, methods of making an antibody library, kits, and methods of generating a bispecific antibody related thereto.